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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNB1
All Species:
22.12
Human Site:
T459
Identified Species:
69.52
UniProt:
Q02641
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02641
NP_000714.3
598
65714
T459
D
Q
P
L
E
R
A
T
G
E
H
A
S
M
H
Chimpanzee
Pan troglodytes
XP_511449
596
65279
T457
D
Q
P
L
E
R
A
T
G
E
H
A
S
M
H
Rhesus Macaque
Macaca mulatta
XP_001086857
598
65671
T459
D
Q
P
L
H
R
A
T
G
E
H
A
S
V
H
Dog
Lupus familis
XP_548150
581
64003
T442
D
Q
S
L
E
R
A
T
G
E
H
A
S
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3Z5
597
65468
T459
D
Q
P
L
D
R
A
T
G
E
H
A
S
V
H
Rat
Rattus norvegicus
P54283
597
65661
T459
D
Q
P
L
D
R
A
T
G
E
H
A
S
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425981
649
73140
R505
N
D
H
S
V
P
E
R
S
N
S
Q
I
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002652
478
52871
I349
P
I
I
V
Y
I
K
I
A
S
P
K
V
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.3
94.6
N.A.
97.6
97.1
N.A.
N.A.
60.4
N.A.
68.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.1
99.5
95.8
N.A.
98.6
98.1
N.A.
N.A.
70.5
N.A.
73.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
100
N.A.
N.A.
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
75
0
13
0
0
75
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
13
0
0
25
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
38
0
13
0
0
75
0
0
0
13
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% G
% His:
0
0
13
0
13
0
0
0
0
0
75
0
0
0
75
% H
% Ile:
0
13
13
0
0
13
0
13
0
0
0
0
13
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
0
% K
% Leu:
0
0
0
75
0
0
0
0
0
0
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
13
0
63
0
0
13
0
0
0
0
13
0
0
0
0
% P
% Gln:
0
75
0
0
0
0
0
0
0
0
0
13
0
0
13
% Q
% Arg:
0
0
0
0
0
75
0
13
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
13
0
0
0
0
13
13
13
0
75
0
0
% S
% Thr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% T
% Val:
0
0
0
13
13
0
0
0
0
0
0
0
13
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _